MTCS for Cancer and AIDS Treatment, A Brief Introduction

摘要

Modified Trichosanthin (MTCS) is a new drug for treating cancer, AIDS and other viral infectionsdeveloped with protein engineering technologies. Its pre-clinical research works were completed by ShanghaiInstitute for Biological Sciences (formerly Shanghai Institute of Cell Biology), Chinese Academy of Sciences.This project is currently seeking partnership world-wide.HIGH ANTI-CANCER ACTIVITY AND LOW TOXICITY MTCS is a powerful inhibitant to a broad variety of human cancer cells, e.g., leukemia, stomach cancer,hepatoma, lung cancer, colon cancer, breast cancer, kidney cancer, melanoma, and brain cancer, etc. Studyresults indicated the presence of MTCS specific binding receptors on the membrane of cancer cells. MTCSinduces cancer cellular apoptosis through binding with these receptors. No such receptor is present on normalbody cells. Therefore no toxic effects in normal body cells can be observed even at a concentration severalhundred times higher than that used in treatments.