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Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease

         

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Dear Editor, Since ZIKV outbreak was first reported in South and Central America and the Caribbean,it has spread to both North America and Asia [1].Preliminary reports have now estimated as many as 1.3 million cases of infection in this widespread epidemic [2].Initially it was thought that the ZIKV only causes mild symptoms such as fever,myalgia,and rash;recent studies have revealed that ZIKV can also cause severe neurological pathologies such as neonatal microcephaly and Guillain-Barre syndrome [3].

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    《细胞研究:英文版》 |2016年第11期|1260-1263|共4页
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