拉贝洛尔联合硫酸镁治疗中重度妊娠高血压综合征临床分析

摘要

目的：观察和分析拉贝洛尔联合硫酸镁治疗中重度妊娠高血压综合征的临床效果。方法选取自2014年6月～2015年6月在我院进行治疗的120例中重度妊娠高血压综合征患者作为研究对象，将其随机分成对照组和观察组，医护人员给予对照组的60名患者进行硫酸镁治疗，而观察组的60名患者在对照组基础上给予盐酸拉贝洛尔治疗，对两组患者治疗前后的平均动脉压（MAP）、全天尿蛋白水平、并发症的发生率以及药物是否存在不良反应进行观察，对照这两组患者的临床效果是否存在差异。结果通过治疗，两组患者MAP、全天尿蛋白水平均低于治疗前，观察组明显低于对照组，两个小组之间比较的差异性有统计学意义（P<0.05）；观察组并发症发生率为8.33%明显低于对照组的23.33%，两个小组之间比较的差异性有统计学意义（P<0.05）；两组患者在治疗期间均未出现严重不良反应。结论通过拉贝洛尔联合硫酸镁的治疗方法，能够有效改善中重度妊娠高血压综合征患者的病症，对提高患者的生存质量具有重要的意义，对腹中胎儿的成长发育未产生影响，值得在临床上进一步推广和采用。%Objective To observe the clinical effect and analysis of labetalol combined with magnesium sulfate in the treatment of severe pregnancy induced hypertension syndrome. Methods since June 2014 to 2015 June in our hospital for treatment of 120 cases of severe pregnancy induced hypertension syndrome patients as the research object, were randomly divided into control group and observation group, the medical staff to give 60 patients in the control group of magnesium sulfate in the treatment, while the observation group of 60 patients given labetalol hydrochloride treatment group on the basis of the control. Before and after the treatment, the patients in the two groups in mean arterial pressure (map), throughout the day, the level of urine protein, complications occurrence rate and drugs the existence of adverse reaction were observed and whether there are differences in the clinical effect of the two groups of patients in the control.Results through the treatment, the two groups of patients with MAP, all day urinary protein levels were lower than before treatment, the observation group was significantly lower than the control group, the difference between the two groups was statistically significant (P<0.05); observation group complication rate was 8.33% was significantly lower than the control group of 23.33%, the difference between the two groups was statistically significant (P<0.05); two groups of patients in the treatment period did not appear serious adverse reactions.Conclusion by labetalol combined with magnesium sulfate treatment can effectively improve severe pregnancy induced hypertension syndrome in patients with the disease and improve the quality of life of patients has important significance. On the fetus growth and development were not affected, it is worth clinical further promotion and application of.