[1]Center for Autoimmune Liver Diseases Humanitas Clinical and Research Center Rozzano20089 Italy;
[2]Department of Biomaterial Science and Technology University of Twente Enschede7500AE The Netherlands;
[3]Department of Clinical and Experimental Medicine University of Florence Florence50141 Italy;
Hepatocellular carcinoma; cholangiocarcinoma; cancer stem cells; tumor heterogeneity; drug-resistance;