Role of Nuclear Import Pathway in Epigenetic Silencing Identified

摘要

On Apr 10th,2018,Dr.ZHU Bing’s lab at the Institute of Biophysics(IBP),Chinese Academy of Sciences(CAS)published a paper entitled"Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing"in PNAS.In this study,they described a regulator,CSE1L,that is essential for the silencing of many endogenous methylated genes,and proposed that the cargo specificity of the