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Calcium phosphate cements for bone engineering and their biological properties

机译:骨工程用磷酸钙水泥及其生物学特性

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摘要

Calcium phosphate cements(CPCs) are frequently used to repair bone defects. Since their discovery in the 1980 s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering. Much effort has been made to enhance the biological performance of CPCs, including their biocompatibility, osteoconductivity, osteoinductivity, biodegradability,bioactivity, and interactions with cells. This review article focuses on the major recent developments in CPCs,including 3 D printing, injectability, stem cell delivery, growth factor and drug delivery, and prevascularization of CPC scaffolds via co-culture and tri-culture techniques to enhance angiogenesis and osteogenesis.

著录项

  • 来源
    《骨研究(英文版)》 |2017年第4期|286-304|共19页
  • 作者单位

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    Center for Stem Cell Biology and Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA;

    University of Maryland Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA;

    Mechanical Engineering Department,University of Maryland Baltimore County, Baltimore, MD 21250,USA;

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China;

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    VIP Integrated Department, Stomatological Hospital of Jilin University, Changchun, Jilin 130011, China;

    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China;

    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China;

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    Volpe Research Center, American Dental Association Foundation,National Institute of Standards&Technology,Gaithersburg,MD 20899,USA;

    Department of Endodontics,Periodontics and Prosthodontics,University of Maryland School of Dentistry,Baltimore,MD 21201,USA;

    Department of Orthopaedic Surgery, Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,China;

    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China;

  • 收录信息 中国科学引文数据库(CSCD);
  • 原文格式 PDF
  • 正文语种 eng
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  • 入库时间 2022-08-19 03:40:30
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