The Impact of Directly Observed Therapy on Preventive Treatment for Latent Tuberculosis Infection among Students in Dalian, China

摘要

Preventive treatment has an essential effect on latent tuberculosis infection （I.TBI） [purified protein derivative （PPD） induration 〉15 mml. Between 2010 and 2013, there were 6 tuberculosis （TB） outbreaks in the universities in Dalian, China. So far, in Dalian, the directly observed therapy （DOT） and full course management （FCM） were widely used in the preventive treatment of LTBI. However, it is yet to be determined which one of them has better efficacy. Therefore, the purpose of our study was to explore the performance of these two strategies for LTBI preventive treatment.