Effects of Endurance and Endurance-strength Exercise on Renal Function in Abdominally Obese Women with Renal Hyperfiltration：A Prospective Randomized Trial

摘要

Objective Obesity is associated with kidney defects.Physical activity is a key element in the treatment of obesity.The aim of this study was to compare the effect of endurance and endurance-strength training on kidney function in abdominally obese women.Methods Forty-four abdominally obese women were randomized to endurance training or endurance-strength training,three times a week for 3 months.Before and after the intervention,kidney function was assessed by measuring blood creatinine,urine creatinine,and urine albumin levels,and the albumin-to-creatinine ratio and glomerular filtration rate(GFR) were calculated.Results Renal hyperperfusion was present in both groups before the study.Following both types of physical activity,similar modifications of the investigated parameters were observed,but with no significant between-group differences.Both courses of training led to a significant increase in blood creatinine and a subsequent decrease in the GFR.A significant increase in urine creatinine and album levels,though not exceeding the range for microalbuminuria,was not accompanied by any difference in the albumin-to-creatinine ratio after endurance-strength training alone.Conclusion Three months of either endurance or endurance-strength training has a favorable and comparable effect on renal function in abdominally obese women with renal hyperfiltration.