During a toxicological test using diisorpopyl methylphosphonate(DIMP)on mallards,an anaesthesia-like response was noted after oral dosing.In order to further elucidate these effects.arterial blood pressures were determined both pre-and post-dosing on adlt male and female mallards by cannulation of the left carotid artery.A significant decrease in systolic,diastolic,and mean blood pressure was noted after the oral administration of DIMP.There was no significant difference in response between males an females.During the first 30min after dosing,systolic pressure fell from an average of 158 mmHg,to 94mmHg,diastolic decreased from 127 mmHg to 63 mmHg,and mean blood pressure droped from 138mmHg to 75mmHg.However,there was no significant effect on pulse pressure,heart rate,or respiratory rate.These results are compared to physiological data cited in the literature for various CNS-acting drugs on mallards.
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