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干眼病理研究进展

     

摘要

干眼是临床上常见的慢性眼表疾病之一,主要以泪膜稳定性下降和眼表组织病变为特征。泪膜成分的改变、基于免疫的炎性反应及神经调节异常等是干眼发生和发展的重要因素。改变基因结构已成为一种新的研究方向,计算机图形处理技术和分子生物学检测技术也逐步用于干眼的研究及诊断。%Dry eye is one of the common chronic disease of ocular surface characterized by the stability of tear film decrease and ocular surface lesion .The change of tear film and the inflammatory reaction which based on immune and the neural regulation abnormality are the important factors in the occurrence , development of dry eye .Alterations in gene structure has become a new research direction , also computer image processing techniques and detection tech-niques of molecular biology gradually have been applying in research and diagnosis of dry eye .

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