Antimicrobial activity of mangrove plant (Lumnitzera littorea)

摘要

Objective:To investigate the antimicrobial activities ofn-hexane, ethyl acetate and methanol extracts of the leaves ofLumnitzera littorea (L. littorea) against six human pathogenic microbes. Methods: The antimicrobial activity was evaluated using disc diffusion and microdilution methods.Results:The antimicrobial activities of the crude extracts were increased with increasing the concentration. It is clear thatn-hexane extract was the most effective extract. Additionally, Gram positiveBacillus cereus (B. cereus) appear to be the most sensitive strain whilePseudomonas aeruginosa (P. aeruginosa) and the yeast strains (Candida albicans (C. albicans) andCryptococcus neoformans (C. neoformans)) appear to be resistance to the tested concentrations since no inhibition zone was observed. The inhibition of microbial growth at concentration as low as0.04 mg/mL indicated the potent antimicrobial activity ofL. littorea extracts.Conclusions:The obtained results are considered sufficient for further study to isolate the compounds responsible for the activity and suggesting the possibility of finding potent antibacterial agents fromL. littorea extracts.