Metabolic syndrome among infertile women with polycystic ovary syndrome

摘要

Objective: To detect the prevalence of metabolic syndrome (MS) among infertile women with polycystic ovary syndrome (PCOS). Methods: Two hundred and twenty infertile PCOS women were included in this prospective cross section study. Diagnosis of PCOS was based on at least two of ESHRE/ASRM criteria and diagnosis of MS was based on at least three of NCEP ATP III criteria. A standard questionnaire was used to document length of menstrual cycles, personal and family history of medical disorders. Signs of androgen excess and insulin resistance were noted in the physical examination. Anthropometric measurements were done to measure waist circumference, hip circumference and body mass index (BMI) was calculated. Overnight fasting blood sample and a 75 gram oral glucose tolerance test, TSH, prolactin, total testosterone, SHBG and lipid profile levels were evaluated in all studied PCOS women. Trans-vaginal ultrasound was also done to measure;ovarian volume and number of follicles in both ovaries. Results: The prevalence of MS in studied PCOS women was 30.5% (67/220). There is strong positive correlation between prevalence of MS and both age and BMI of the studied PCOS women. Logistic regression analysis showed that;the age>25 and waist-hip ratio≥0.85 were powerful predictors for the prevalence of MS in PCOS women. Conclusion:The prevalence of MS was 30.5%in the studied PCOS women. The age above 25 years and waist-hip ratio≥0.85 were powerful predictors for prevalence of MS in PCOS women.