Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow

摘要

The effects of the renal artery stenosis(RAS) on the blood flow and vesselwalls are investigated.The pulsatile blood flow through an anatomically realistic model ofthe abdominal aorta and renal arteries reconstructed from CT-scan images is simulated,which incorporates the fluid-structure interaction(FSI).In addition to the investigationof the RAS effects on the wall shear stress and the displacement of the vessel wall,it isdetermined that the RAS leads to decrease in the renal mass flow.This may cause theactivation of the renin-angiotension system and results in severe hypertension.