3-65 Effects of Carbon Monoxide-releasing Molecule (CORM-3) on Zebrafish Embryos Induced by X-rays*

摘要

CO is increasingly appreciated as a signal molecule, due to its protective features, such as anti-inflammatoryfunction[1], anti-apoptosis[2]. Carbon monoxide -releasing molecules (CORMs) represent a group of compounds thatare capable of modulating physiological functions via liberating CO. Among various CORMs synthetized, CORM-3is one of the most promising compounds because it is soluble in water and the half-life to liberate CO in saline was10.6 h, thus imitating the action of CO more closely[3].