Effects of 'Xinsanxian' on Growth Performance of Piglets and Immune Effect of Swine Fever Vaccine

摘要

cqvip:[Objective] The paper was to study mixed feed additives that could prevent and control diarrhea, improve piglet production performance and immune function, and substitute for antibiotics.[Method] Totally 100 healthy weaning piglets with an average age of 21 days were divided into five groups(half male and half female, similar weight), and additives were mixed in feed. Group A was added with Xinsanxian I composed of Xin-changtai, acidifier, suckling pig enzyme, etc.;group B was added with Xinsanxian II composed of Xinchangtai, Bacillus subtilis, yeast, etc.;group C was added with Xinsanxian III composed of Xinchangtai, fructooligosaccharide, suckling pig enzyme, etc.;group D was added with Jiaosanxian composed of hawthorn, malt, medicated leaven, etc.;group E was set as blank control group. Feed intake was recorded in columns throughout the exper-iment. Fasting piglets were weighed at the beginning(28 days of age) and the end(70 days of age) of the test, and the average daily weight gain(ADG), average daily feed intake(ADFI), feed gain ratio(F/G) and diarrhea rate of each piglet were calculated. Five piglets were randomly selected from each group before immunization, at 2 weeks post immunization, at 4 weeks post immunization and at 6 weeks post immunization, respectively.Approximately 2 mL of blood samples were collected from anterior vena cava, and the content of swine fever antibody was determined by ELISA.[Result] In terms of improving the growth performance of weaning piglets and preventing and controlling diarrhea, groups A and C had significantly better effects than groups B and D, all of which had significantly better effects than group E. The antibody titers of swine fever in group B and group C were significantly higher than those in group A and group D, all of which were significantly higher than that in group E( P<0.05).[Conclusion]Addition of Xinsanxian in the diet enhanced the immune effect of piglet swine fever vaccine, and improved the antibody titer. Moreover, it signifi-cantly increased the daily gain of weaning piglets, and reduced weight gain ratio and diarrhea rate. Xinsanxian III received the best effort.