[Objective] The research aimed to study the quality standard of Compound Quanchangning Capsule. [Method]Coptis,Phellodendron,Pulsatilla and Astragalus in Compound Quanchangning Capsule were indentified qualitatively by thin layer chromatography( TLC),and the content of berberine hydrochloride was determined by high performance liquid chromatography( HPLC),to study the quality standard of Compound Quanchangning Capsule. [Result]TLC identification showed that the tested product was clear and well-separated with no interference. Berberine hydrochloride showed a good linear relationship with peak area at the injection volume of 10. 92- 163. 74 μg / m L,and the regression equation was Y = 39 611X- 2 387. 9( R2= 0. 999 8); the average recovery was 97. 60%,and the relative standard deviation was 1. 64%( n = 6). [Conclusion] The standard is simple in operation and good in specificity,stability and repeatability,which is prompted as a favorable method for quality control of Compound Quanchangning Capsule.
展开▼
