Polymorphism of POMC Gene in Guizhou Yellow Cattle

摘要

[Objective]The paper was to explore the effect of pro-opiomelanocortin (POMC) on feeding behavior and energy homeostasis of animals.[Method]Using DNA sequencing technology,polymorphisms of POMC gene in 92 individuals of Guizhou yellow cattle were studied.[Result]Five mutation sites,138 C> T,430 C> T,644 C> T,668 C> T,693 A> G,were found in the 870 bp amplification product.Polymorphism results showed that except the mutation site 430 C>T that was deviated from the Hardy-Weinberg equilibrium (HWE) state (P0.05); the peptide information content (PIC) of five mutation sites were moderate polymorphism.[Conclusion]The POMC gene of Guizhou Yellow Cattle was abundant in genetic diversity,with great selection potential,which could be used as a potential genetic marker of cattle growth traits.