交感型颈椎病尿液去甲肾上腺素浓度水平的初步临床研究

摘要

Objective To preliminarily discuss the change of urine noradrenoline levels in urine of patients with sympathetic type of cervical spondylosis.Methods To determine the noradrenoline concentrations in urine in the case, the control and the normal groups.Meanwhile, we also scored the case group according to , and evaluated the rank of the cases based on three grades (mild, moderate and severe , respectively).Results The noradrenoline con-centractions in urine in the normal group were not significantly different from the control group (P >0.05).Besides, the noradrenoline concentractions in urine in the case group were significantly different from both the control and the normal groups (P <0.001).The noradrenoline concentractions in urine of mild, moderate and severe grade groups were significantly different (P <0.001).Con-clusions The urine noradrenoline levels could be treated as a quantitative indicator to clinically diagnose sympathetic type of cervical spondylosis.%目的：初步探讨交感型颈椎病患者尿液去甲肾上腺素浓度水平的变化。方法分别测定病例组、对照组及正常组尿液中的去甲肾上腺素浓度，同时对病例组根据《颈椎病临床评价量表》进行评分，按照轻、中、重度三个等级评价。结果正常组尿液去甲肾上腺素浓度与对照组尿液去甲肾上腺素浓度无显著性差异（P ＞0．05），病例组与正常组及对照组尿液去甲肾上腺素浓度差异有显著性（P ＜0．001），轻度组、中度组和重度组尿液去甲肾上腺素浓度有显著性差异（P ＜0．001）。结论尿液去甲肾上腺素浓度水平或可作为交感型颈椎病临床诊断的一个量化指标。