安阳地区无偿献血者及其中男男性行为人群HIV感染情况调查分析

摘要

目的 调查分析安阳地区无偿献血者及其中男男性行为(MSM)人群人类免疫缺陷病毒(HIV)感染情况.方法选取2008年1月至2015年12月安阳市中心血站440474例无偿献血者血液标本,使用酶联免疫吸附实验(ELISA)和免疫印迹法进行抗-HIV初筛与确证试验,调查分析MSM感染HIV的献血者相关资料,分析HIV感染率及初次献血和重复献血人群感染情况.结果 440474例无偿献血者中,共检出抗-HIV阳性献血者33例,HIV感染率为0.0075%;其中,通过MSM感染HIV 7例,占21.21%;MSM感染 HIV人群结构特征:年龄18 ~29岁占85.71%,大学以上学历占57.14%,在校学生占42.86%,未婚占85.71%;与历年HIV感染率比较,总体呈现上升趋势,差异无统计学意义(χ2=7.49,P>0.05);初次献血者MSM人群HIV感染率高于重复献血者,差异有统计学意义(χ2=8.54,P<0.05).结论 安阳地区无偿献血者HIV感染总体呈平稳低流行趋势,初次献血者MSM人群HIV感染率高于重复献血者.%Objective To investigate the infection situation of human immunodeficiency virus(HIV)in men who had sex with men (MSM)among the voluntary blood donors in Anyang area.Methods The blood samples of 440 474 voluntary blood donors in Anyang area, collected in our blood station from Jan 2008 to Dec 2015,were detected for anti -HIV primary screening and validation testing by means of enzyme-linked immunosorbent assay(ELISA)and Western blotting(WB).Based on the data of blood donors with HIV infection in the MSM group,the prevalence rate of HIV infection and infection situation in these donors of first and repeated donation were investigated and analyzed.Results Among the 440 474 voluntary blood donors,a total of 33 anti-HIV positive blood donors were found,with a prevalence rate of 0.007 5%,and among which 7 donors with HIV infection were MSM,accounting for 21.21%.As for the population structure charac-teristicsof 33 donors,cases of 18~29 years old accounted for 85.71%,cases with university degree accounted for 57.14%,cases of school students for 42.86%,and unmarried cases for 85.71%.The prevalence rate of HIV infection in each year showed an increasing trend and the differences among them were not significant(χ2=7.49,P>0.05).There were significant differences in the MSM HIV infection rate the blood donors of first higher repeated donation(χ2=8.54,P<0.05).Conclusion The overall HIV infection among those voluntary blood donors in Anyang area presents a steady, low prevalence tendency, and in the MSM population, the blood donors of first donation have higher HIV infection rate than those of repeated donation.