钕在涡虫体内的蓄积及其毒理学分析

摘要

In this study, the bioaccumulation and toxicity of neodymium (Nd) in pla-narian Dugesia japonica were investigated. The results showed that with the in-creasing dietary Nd supplementation, the concentration of Nd in the planarian showed a significant linear increase and the balance of mineral elements was bro-ken with the decrease of Ca, Fe and Mo, and the increase of K and Mg. The content of soluble proteins and the activities of superoxide dismutase (SOD) and catalase (CAT) decreased with the increase of Nd concentration, while the content of H2O2 rose gradual y. The mortality was directly proportional to the Nd concentra-tion. The results indicated that planarian is a very sensitive aquatic animal to Nd contamination and can be an indicator organism for Nd pol ution.%以东亚三角涡虫为试验材料，以钕为胁迫因子，研究了不同浓度（0、0.05、0.1、0.2、0.4 mmol/L）的钕在涡虫体内的蓄积及其毒理学作用。结果表明，随着外源钕浓度的增大，涡虫体内的钕逐渐蓄积，且产生明显的矿质营养代谢失衡，主要表现为显著降低了涡虫体内Ca、Fe和Mo含量，增加了 K和 Mg吸收。涡虫体内的可溶性蛋白含量以及超氧化物歧化酶和过氧化氢酶活性随着钕浓度的升高逐渐降低，涡虫体内的抗氧化酶系统的动态平衡被打破， H2O2逐渐积累。随着钕浓度的逐渐升高，涡虫的死亡率逐渐增大，高浓度下，涡虫逐渐解体死亡。由此可见，涡虫是一种对钕污染非常敏感的水生动物，在水体钕污染检测方面具有潜在价值和应用前景。