冠状动脉慢血流现象病理生理机制及治疗进展

摘要

In coronary angiography,there is often no stenosis or no obvious stenosis in the epicardial coronary artery,but the filling and emptying velocity of contrast agent in the coronary artery is obviously delayed.This phenomenon is called coronary slow flow phenomenon (CSFP).The clinical features are recurrent chest pain,electrocardiogram or load electrocardiogram often with myocardial ischemia.Although coronary angiography show coronary artery no stenosis,but it more likely to suffer from coronary atherosclerosis and obstructive coronary artery disease.Therefore,CSFP is not a completely benign condition,caused a lot of cardiologists,concern in recent years.However,the etiology, pathogenesis,risk factors,treatment and prognosis of the disease are still lack of a large number of studies,and this paper reviews the current research status of slow blood flow phenomenon.%在冠状动脉造影检查中,常碰到心外膜下冠状动脉无狭窄或无明显狭窄,但造影剂在冠状动脉内充盈及排空速度明显延迟,这种现象称为冠状动脉慢血流,其临床特点是反复胸痛,心电图或负荷心电图常有心肌缺血征象,尽管冠状动脉造影显示冠状动脉无狭窄,但更容易患冠状动脉粥样硬化及阻塞性冠状动脉疾病,因此,慢血流不是一个完全良性的疾病,近年来引起许多心内科医师的关注,而冠状动脉慢血流的发病原因、发病机制、危险因素、治疗、疾病预后等尚缺少大量的研究,现针对慢血流现象相关研究的现状进行综述.