糖尿病动物模型心功能评价方法

摘要

糖尿病心血管并发症（ cardiovascular complications of diabetes ， CCD）是糖尿病患者最主要的死亡原因，其中糖尿病心肌病（ diabetic cardiomyopathy ， DC）是心力衰竭的主要原因。对于分析糖尿病心肌病的机制、早期诊断以及改进和优化治疗，心脏功能评估起到重要桥梁作用，而糖尿病动物模型直接或间接反映糖尿病的发生和发展过程，是一个良好的研究载体。本文旨在综述国内外糖尿病动物模型心脏功能评价的重要方法。%Cardiovascular complication of diabetes ( CCD) is a leading cause of mortality in diabetic patients , and diabetic cardiomyopathy ( DC) vastly accounts for heart failure in those CCD patients .In the research of pathogenesis , early diagnosis and better treatment of DC , cardiac function evaluation plays a key bridging role .Addtionally , animal models may well simulate the development of diabetes .The purpose of this article is to review the important methods in evaluating heart function of diabetes animal models .