Objective To report the response of an epilepsy patient to photic stimulation of intracranial electrodes. Methods A patient with refractory epilepsy was assessed with SEEG before operation. Electrodes were implanted into different sites of occipital-temporal lobes. The opened or closed eyes of the patient were stimulated with light source at the frequency of l-40Hz. Results All the significant contacts of physiological light-driven electrodes, located in the medial occipital lobe, were close to the calcarine fissure. The photo-effect was different at different contacts of intracranial electrodes due to different distances to the calcarine fissure. No pathological photo-effect was observed. Conclusion Much precise physiological information on the physiological visual system of epilepsy patients can be obtained by implanting electrodes into their brain, especially into the medial occipital lobe.%目的 报告1 例癫痫病人脑内电极对闪光刺激的反应.方法 1 例部分性难治性癫痫病人在术前评估时利用立体定向技术,在枕- 颞叶脑组织内不同部位置入电极,病人处于睁眼或闭眼状态,使用1-40Hz 频率的光源刺激.结果 出现明显生理性光驱动的电极接触点全部处于枕叶内侧面,靠近距状裂,但不同的电极接触点由于位于距状裂上下及距离其远近不同,出现生理光驱动的效果不同,未发现病理性光效应.结论 通过癫痫病人脑内电极的置入,特别是在枕叶内侧面置入脑内电极,可以得到确切的关于视觉系统的生理信息.
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