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Towards a fluid solid interaction model of a dynamic lung.

机译:建立动态肺的流体固体相互作用模型。

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摘要

Because the pulmonary system is a site for both environmental particulate contamination, as well as drug delivery into the body, numerous research groups have focused on precisely understanding its inner-workings. Past research has demonstrated the need to realistically model the lung walls in order to accurately capture the complex airflow profile throughout all of the branches. Since this is paramount to properly replicating particulate transport in the lung, computational fluid dynamics simulations on their own are inadequate, as they cannot account for lung wall dilation. Only by coupling the fluid and solid domains can natural lung behavior can be effectively modeled.;The goal of this work was to develop and validate the methods required to create a reliable computational fluid-solid interaction pulmonary simulation. To validate the proposed technique, a balloon was both experimentally and computationally modeled. A small pulmonary system was then presented to demonstrate the simulation capabilities.
机译:由于肺部系统既是环境微粒污染的场所,也是药物向人体输送的场所,因此许多研究小组都致力于精确地了解其内部结构。过去的研究表明,需要对肺壁进行逼真的建模,以准确捕获整个分支的复杂气流分布。由于这对于正确复制肺中的颗粒运输至关重要,因此,仅靠计算流体动力学模拟是不够的,因为它们不能解释肺壁扩张的情况。只有通过将流体域和固体域耦合,才能有效地模拟自然肺行为。这项工作的目的是开发和验证创建可靠的计算流体-固体相互作用肺模拟所需的方法。为了验证所提出的技术,对气球进行了实验和计算建模。然后提出了一个小型的肺系统以演示模拟功能。

著录项

  • 作者

    Jacobs, Justin C.;

  • 作者单位

    University of Denver.;

  • 授予单位 University of Denver.;
  • 学科 Engineering Mechanical.;Biophysics Biomechanics.
  • 学位 M.S.
  • 年度 2012
  • 页码 88 p.
  • 总页数 88
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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