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Numerical study of a viscoelastic model for hydrocephalus.

机译:脑积水粘弹性模型的数值研究。

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摘要

Hydrocephalus is a clinical condition where the brain tissue is deformed by the expanding ventricules. In this thesis, the mechanical deformation of a hydrocephalic brain is studied using a biomechanical model, where the material properties of the tissue are described by a viscoelastic model. A set of governing equations is derived when the motion is quasi-static motion and deformation is small. Then, finite element method is used for spatial discretization, and finite difference and trapezoidal rule are used for time-stepping. Moreover, the computational meshes are generated from medical images of patient's brain using level set method and a program called DistMesh. Numerical stability of the time-stepping scheme is also studied.; Several numerical studies are conducted to investigate several aspects of the brain with hydrocephalus. The state of stress of the tissue is found to be compressive everywhere in the brain. The viscoelastic properties of the brain are investigated and found to be dominated by elastic response. Lastly, the displacement made by the ventricular wall as it expands and shrinks is found to be non-uniform.
机译:脑积水是一种临床状况,脑组织因心室扩张而变形。本文采用生物力学模型研究脑积水的机械变形,通过粘弹性模型描述组织的物质特性。当运动为准静态运动且变形较小时,得出一组控制方程。然后,将有限元方法用于空间离散化,并将有限差和梯形规则用于时间步长。而且,计算网格是使用水平集方法和称为DistMesh的程序从患者大脑的医学图像生成的。还研究了时间步进方案的数值稳定性。进行了一些数值研究来研究脑积水的大脑的几个方面。发现组织的压力状态在大脑中的任何地方都是压缩性的。研究了大脑的粘弹性,并发现其受弹性反应支配。最后,发现心室壁在其膨胀和收缩时产生的位移是不均匀的。

著录项

  • 作者

    Lee, Jenny H. M.;

  • 作者单位

    University of Waterloo (Canada).;

  • 授予单位 University of Waterloo (Canada).;
  • 学科 Mathematics.
  • 学位 M.Math.
  • 年度 2006
  • 页码 119 p.
  • 总页数 119
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 数学;
  • 关键词

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