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Airsickness treatment and prevention: Recommendations regarding antiemetics and/or acustimulation.

机译:晕机的治疗和预防:有关止吐药和/或止痛药的建议。

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摘要

Airsickness has been an important concern for aviation since before World War II. Airsickness is still a topic of serious discussion in the aviation community, despite recent advances in medical science, aircraft engineering and performance. Symptoms of motion sickness range from mild to incapacitating in nature and can cause degradation in performance measures of reaction time, postural stability and cognitive functioning. This can result in unacceptable work force losses, incur significant costs, and ultimately result in mission compromise and/or missing critical objectives. Current pharmacological interventions may produce side effects such as sedation and diminished cognition.;Acustimulation at the median P6, or Neiguan, point has recently generated interest as a non-pharmacological means of preventing motion sickness. A recent study evaluating a popular acupressure wristband reported it to be effective in the suppression of the major symptoms (nausea and vomiting) of motion sickness. This study concluded that continuous vigorous stimulation of the P6 point was required to achieve a significant benefit. The commercially available ReliefbandRTM provides electrical acustimulation at the P6 point thereby reportedly countering symptoms of chemotherapy-induced nausea and vomiting. Its makers market it as "the only FDA-cleared device for motion sickness". A literature search revealed that no published studies comparing currently available pharmacologic and non-pharmacologic (ReliefbandRTM) motion sickness treatments in conjunction with rotary wing operations are available.;This capstone describes a randomized, double blind, cross over study comparing the effectiveness of four airsickness countermeasures to a placebo control and to each other on reaction time, postural stability, and cognition in relation to airsickness symptom severity and their ability to ameliorate performance declines following simulated rotary wing combat operations. The data suggest that only the combination of phenergan with caffeine was effective in achieving these measures. This study will help enable the aerospace medical community to make recommendations to military commanders and civilian policy makers concerning the ability of viable treatments to mitigate performance decrements seen because of rotary wing flight induced motion sickness.
机译:自第二次世界大战以来,晕机一直是航空业的重要问题。尽管最近在医学,飞机工程和性能方面取得了进步,但晕机仍是航空界认真讨论的话题。本质上,晕车的症状从轻度到丧失工作能力,会导致反应时间,姿势稳定性和认知功能的表现指标下降。这可能导致无法接受的劳动力损失,产生大量成本,并最终导致任务折衷和/或缺少关键目标。当前的药物干预可能会产生诸如镇静作用和认知功能下降之类的副作用。;在中位P6或内关点进行刺激最近引起了人们的兴趣,将其作为预防晕动病的非药物手段。最近一项评估流行的指压腕带的研究报告说,它可有效抑制晕车的主要症状(恶心和呕吐)。这项研究得出结论,需要持续大力刺激P6点才能获得明显的益处。市售的ReliefbandRTM在P6点提供电刺激,据报道可抵抗化疗引起的恶心和呕吐症状。它的制造商将其称为“唯一经FDA批准的晕车设备”。文献检索显示,尚无已发表的研究比较现有的药物和非药物(ReliefbandRTM)运动病与旋转翼手术相结合的治疗方法;该顶点描述了一项随机,双盲,交叉研究,比较了四种晕机的有效性在模拟旋翼战斗行动之后,对晕机症状严重程度及其对改善症状的能力的反应时间,姿势稳定性和认知能力方面,对安慰剂对照和彼此采取对策。数据表明,只有phenergan和咖啡因的组合才能有效实现这些措施。这项研究将帮助航空航天医学界向军事指挥官和民用政策制定者提出建议,说明可行的治疗方法可减轻由于旋翼飞行引起的晕车而导致的性能下降。

著录项

  • 作者

    Phelps, Shean Eric.;

  • 作者单位

    The University of Texas Medical Branch Graduate School of Biomedical Sciences.;

  • 授予单位 The University of Texas Medical Branch Graduate School of Biomedical Sciences.;
  • 学科 Public health.;Pharmacology.
  • 学位 M.P.H.
  • 年度 2007
  • 页码 71 p.
  • 总页数 71
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-17 11:40:07

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