声明
Chapter 1 Introduction
1.1 Biomaterials
1.2 Introduction to Silicones
1.2.1 History of silicone chemistry
1.2.2 Nomenclature of silicones
1.2.3 Classification of silicones
1.2.4 Silicone elastomer applications
1.3 Polyurethane elastomer (PU)
1.3.1 Introduction to Polyurethane Elastomers
1.3.2Classification of Polyurethane Elastomers
1.3.3 Application of polyurethane elastomer
1.4 Polysiloxane-polyurethane block copolymer
1.4.1 Introduction to polysiloxane-polyurethane block copolymer materials
1.4.2Classification of polysiloxane-polyurethane materials
1.4.3Applications of Polysiloxane-polyurethane block copolymer
1.4.4Problems and solutions polysiloxane-polyurethane copolymerization
1.5 Surface modification silicone rubber
1.5.1 Plasma treatment
1.5.2 UV treatment
1.5.3 Chemical Vapor Deposition (CVD)
1.5.4 Layer self-assembly
1.5.5 Coating with metals and metal oxides
1.5.6 Silanization
1.5.7 Sol–gel coating
1.5.8 Deliberate protein adsorption
1.5.9 Dynamic surface modification
1.7 Research significance and thesiscontent
Chapter 2 Hydrophilic Surface Modification of Polydimetylsiloxane-co-2-Hydroxyethylmethacrylate (PDMS-HEMA) by Silwet L-77 (Heptamethyltrisiloxane) Surface Treatment
2.1 Introduction
2.2 Experimental Section
2.2.1 Materials
2.2.2 Synthesis of PDMS-HEMA films
.2.3 Fourier Transform Infrared (FTIR) Spectroscopy
2.2.4 Hydrophilic Surface Modification of PDMS-HEMA films
2.2.5 Transparency measurement
2.2.6 Equilibrium water content measurement
2.2.7 Measurement of Contact Angle
2.2.8 Measurement of Surface Morphology and Elemental Composition
2.2.9 Measurement of Surface Roughness
2.2.10 Mechanical Properties
2.2.11 Protein adsorption experiment
2.3 RESULTS AND DISCUSSION
2.3.1 Fourier Transform Infrared (FTIR) Analysis
2.3.2 Water Contact Angle (WCA) Analysis
2.3.3 Water Contact Angle as a function of time
2.3.4 Transparent measurements
2.3.5 Surface morphology
2.3.6 Surface Roughness Analysis
2.3.7 Equilibrium water content analysis
2.3.8 Mechanical properties analysis
2.3.9 Protein adsorption analysis (PAA)
2.4 Conclusion
Chapter 3 Robust Solvent-free Fabrication and Characterization of (Polydimethylsiloxane-co-2-Hydroxyethylmethacrylate) Poly(ethylene glycol) methacrylate (PDMS-HEMA) PEGMA hydrogels
3.1 Introduction
3.2 Experimental Section
3.2.1 Materials
3.2.2 PDMS-HEMA macromerpre paration
3.2.3 Preparation of the PDMS-HEMA-PEGMA block-polymer network
3.2.4 Network Confirmation
3.2.5 Surface Characterization
3.2.6 Measurement of Equilibrium Water Content (EWC)
3.2.7 The mechanical properties
3.2.8 Thermal Analysis
3.2.9 Transparency measurement
3.2.10 Internal Morphology Characterization
3.2.11 Protein adsorption analysis
3.3 Results and discussion
3.3.1 ATR-FTIR characterization
3.3.2. Surface Characterization
3.3.3 Optical properties
3.3.4 Equilibrium Water Content (EWC) as function of PEGMA content
3.3.5 Evaluation of Phase Separation
3.3.6 Mechanical Properties Analysis
3.3.7 Thermal gravimetric analysis (TGA)
3.3.8 Evaluation of protein adsorption
3.4 Conclusion
Chapter 4 Robust pH, Solventand Solution Composition Reusable Silicone Hydrogels
4.1 Introduction
4.2 Experimental Section
4.2.1 Reagents
4.2.2 Synthesis of Silicon hydrogel
4.2.3 Swelling ratio (SR) measurement
4.2.4 Characterization
4.3 Results and Discussion
4.3.1 Swelling responses of the silicone hydrogels in response to different stimuli
4.3.2 Actual detecting results of responsive hydrogel
4.4 Conclusion
Chapter 5 Conclusion
参考文献
致谢
List of Publications
