Abstract: sult of a resurgence of interest in analytical ultracentrifugation a new instrument, the Beckman XLA, was released recently. This instrument automates spectrophotometric measurements of the concentration distribution of molecules in a gravitational field. In order for the intrinsic merits of analytical ultracentrifugation to be realized fully, this instrument must also include a Rayleigh interference optical system. A prototype design and preliminary performance test of a Rayleigh interferometer for the XLA ultracentrifuge is described here. !11
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