Spatiotemporal Temperature and Cell Viability Measurement Following Laser Therapy in Combination With Carbon Nanohorns

摘要

Inclusion of SWNHs in laser therapy significantly enhances temperature elevation and increases tumor cell destruction. The combination of high resolution spatiotemporal temperature measurements and spatial viability measurements will provide important gemometric heat generation and tumor response information necessary for planning SWNH-mediated laser therapies, whose treatment areas must be strictly controlled. It is believed that these measurement toools will result in more effective SWNH-mediated laser therapies. Future work will measure the spatiotemporal temperature and cell viability of tumor cell containing phantomsrn1. Miyako E, Nagata H, Hirano K, Makita Y, Nakayama K, andrnHirotsu T. Near Infrared Laser triggered Carbon Nanohorns for selective elimination of microbes. Nanotechnology 2007; 18:475103-475110.rn2. Geohegan D, Puretzky A, Ivanov I, Eres G, Liu Z, Barnett D, HurnH, Zhao B, Cui H, Rouleau C, Jesse S, Britt P, Christen H, Xiao K, and Fleming P. Laser-Based Synthesis, Diagnostics, and Control of Single-Walled Carbon Nanotubes and Nanohorns for Composites and Biological Nanovectors. Photon-based Nanoscience and Nanobiotechnology 2006:205-223.