MULTI-LAB EVALUATION OF HIP SIMULATOR TEST CONDITIONS ON RELATIVE WEAR RATES OF CROSSLINKED POLYETHYLENES

摘要

Hip wear simulations are an effective method to assess the clinical potential of crosslinked relative to conventional UHMVVPE materials. In general, recently published short and mid term clinical studies for crosslinked and conventional UHMWPE indicate good agreement with simulation results. '' However, there remain substantial differences in the preferred test conditions among laboratories internationally. This study investigated the effect of test conditions from 3 test centers on the wear of conventional and crosslinked poly ethylenes. To permit comparisons, each center included common UHMWPE materials, and multiple serum protein concentrations. Conditions unique to each test center, including load magnitude and profile, simulator kinematics and serum chamber volume were unaltered from their earlier studies.