Fabrication of tissue-engineered blood vessel using electrospinning

摘要

This study shows that electrospun scaffolds exhibit structure and mechanical behavior similar to native vessels. The results also indicate a favorable interaction between this synthetic nanofibrous scaffold with two different types of vascular wall cells. Electrospun vascular scaffolds possess components and distribution similar to normal vessels. Collectively, this study demonstrates the promise of electrospinning as an effective fabrication process for cardiovascular grafts.