Biomechanics and Bioresorbable Material Study toward Pelvic Organ Prolapse Corrective Mesh Design

摘要

Tensile tests using Instron were previously performed at UTSW [2], however attaining large samples for the runs was found to be difficult and the non-physiologic break point tests unreliable. DMA requires minimal sample size, and can reach lower frequencies that mimic physiological strains. Biaxial data is important in understanding tissue mechanical properties. To our knowledge we are the first to perform such tests. Also, different Mns of PLA were successfully synthesized by varying catalyst concentrations. Novel bioresorbable material design must mimic, to the best of its ability, the surrounding tissue characteristics.