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Differentiation of Human Bone Marrow Mesenchymal Stem Cells on Decellularized Extracellular Matrix Materials

机译:人骨髓间充质干细胞在脱细胞的细胞外基质材料上的分化

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Mesenchymal stem cells grown on decellularized porcine dermis or mesothelium do not spontaneously differentiate despite the biological activity of these materials. Induced MSCs will differentiate into osteoblasts or adipocytes on the ECM materials. Bone marrow derived MSCs may serve as a source of autologous cells for pre-seeding these extracellular matrix materials prior to implantation.
机译:尽管这些材料具有生物活性,但在脱细胞的猪真皮或间皮上生长的间充质干细胞不会自发分化。诱导的MSC将在ECM材料上分化为成骨细胞或脂肪细胞。骨髓来源的MSC可以用作自体细胞的来源,以便在植入前预先播种这些细胞外基质材料。

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