Fabrication of Dual-Functional Electrospun Nanofiber Scaffolds for Liver Tissue Engineering

摘要

By taking advantage of the porous and layer-forming properties of electrospun nanofibers, we have designed a dual functional scaffold that induces two different biological responses from hepatocytes. The P450 function of the hepatocytes increased with the amount of 3Mc loading in the scaffolds. The mode of release of 3Mc to primary rat hepatocytes cultured on this dual function scaffold remains to be elucidated.