Maintaining Mixed Populations of Adult Stem Cells Enhances Osteogenic Potential

摘要

TRCs expanded as mixed cell cultures result in a cell population with increased osteogenic potential compared to stromal cell only cultures from the same source of bone marrow-derived cells. This suggests the hypothesis that increased osteogenic potential of mixed cell cultures may be due to signaling between the various stem cell populations, their progenitors and more mature cells acting as accessory "enhancing" cells.