Wet spinning and Characterization of Collagen Fibers Incorporating Hydroxyapatite in Mixed and Coated Form

摘要

Thermal analysis proved that HA had a poor mechanical loading property. However, since HA has high melting temperature, the fibers incorporated with HA could withstand higher temperatures at a constant load of 1N before breaking and had high weight retention at the temperature of 350℃.rnThese results indicate that the amount of HA deposited on the coated fibers was less than the HA present in the composite fibers. This study showed a new technique for coating HA crystals on Cg fibers. Wet spinning for the composite fibers was employed for the first time. A good experiment will be to test the osteoconduction and osteoinduction properties on these fibers. Also, it is necessary to increase the strength of the fibers by crosslinking them with different agents without decreasing the percentage of HA in the fibers. HA Coated Cg fibers with biomimetic methods such as simulated body fluid and the coated fibers obtained from the present study need to be compared. Methods for the uniform dispersion of HA in Cg fibers are to be investigated.