Double Compartment Cellular Automata Modeling of HIV Proliferation Under Plasmapheresis Treatment

摘要

In this work, we apply the Monte Carlo Cellular Automata Simulation technique to study the dynamics of human immunodeficiency virus (HIV) proliferation and the action of virus-immune system in the human body in fighting the disease. Double-compartment model is utilized to take into account the blood as well as the lymph node compartments. Efficacy of treatments by plasmapheresis and its and combination with drug prescriptions are studied. We investigate the impacts of different treatment protocols on the ability of the infected patients to fight the development of AIDS symptoms. In particular, the possibility of interrupted or alternate treatment will be illustrated by CA simulations with appropriately chosen system parameters.