Characterization of Acetylcholine Hydrolysis under Continuous and Pulsed Microwaves Radiation Using Broadband Dielectric Measurement

摘要

In this paper, we will describe the statement of our current advance in continuous and pulsed wave analysis on AchE activation. Acetylcholinesterase (AchE) is a major enzyme that catalyzes the hydrolysis of the neurotransmitter Acetylcholine into Choline and Acetic Acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. In a more general way, it controls nervous and neuromuscular impulses in mammalians species. We will try to determine how continuous waves (CW) or Pulsed Waves (PW) interact with this polarized entity. Dielectric relaxation determination in real time, will give us information about the synthesis output, and power density measurement, the energy activation threshold.