Multicenter clinical trial of itraconazole in the treatment of pulmonary aspergilloma

摘要

Itraconazole 100-200mg was orally administered to 49 patients with pulmonary aspergilloma once a day in principle immediately after breakfast. drug concentrations in fungus balls and in aspergilloma cavities were determined in each measurable case and the data were evaluated in terms of efficacy and afety.