Microsynteny Analysis between the Tomato and Grape Genome

摘要

The tomato and grape are two important model species for studying fruit development and ripening.They belong to two families,Solanaceae and Vitaceae,respectively.The efforts for constructing their genetic and physical maps provide an opportunity for comprehensively comparing genetic maps and physical maps and discovering synteny relationship across the genomes,especially for some conserved regions related to the fruit development and ripening.Here we report the synteny detection between these two species,including details about macrosynteny at the chromosome level and microsynteny within blocks.No macrosynteny was discovered,when 2189 mapped markers in a tomato genetic map were compared with a grape physical map.We further detected microsyntenic regions by comparing sequences from tomato and grape physical maps.We detected 110 syntenic blocks with two homologous pairs and 277 syntenic blocks with more than two homologous pairs.The synteny between tomato and grape was fragmentary and composed a synteny network among different chromosomes or BAC contigs.Additionally,we discovered 3 syntenic blocks which were specially associated with fruit development and ripening.Microsyntenic genes identified in the present study will benefit further research on the fruit development and ripening between two distantly relative species.In order to justify that the syntenic blocks were not detected by chance,we performed a simulation analysis for each comparisan.