Yield Improvement of Pen-G Whole Broth to Make 6-APA OR 7-Adca by Membrane Filtration Systems

摘要

Penicillin G, a beta-lactam antibiotic, is typically present in the fermentation at levels about 50,000 units/ml. The volumetric solids or packed cell volume (PCV) after laboratory centrifugation can range from 30-60