首页> 外文会议>Physics of Medical Imaging pt.2; Progress in Biomedical Optics and Imaging; vol.7 no.28 >Single-photon spatial and energy resolution enhancement of a columnar CsI(Tl) / EMCCD gamma-camera using maximum-likelihood estimation
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Single-photon spatial and energy resolution enhancement of a columnar CsI(Tl) / EMCCD gamma-camera using maximum-likelihood estimation

机译:使用最大似然估计的圆柱CsI(Tl)/ EMCCD伽马相机的单光子空间和能量分辨率增强

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We examined the spatial resolution of a columnar CsI(Tl), single-photon imaging system using an approach that estimates the interaction position to better than the spread of the light distribution. A columnar scintillator was directly coupled to a 512x512 electron multiplying CCD (EMCCD) camera (16 urn pixels) binned at 2x2 to sample at 32 um pixels. Optical photons from gamma-ray/scintillator interactions are sampled over multiple pixels. Resultant images show clusters of signal at the original interaction site, clusters from Cs & I K x-rays up to several hundred microns away, and clusters from collimator K x-rays. Also evident are depth-of-interaction effects which result in a broadening of the light distribution. These effects result in a degradation of spatial and energy resolution. Cluster pixel data was processed to better estimate the interaction position within the initial interaction cluster. Anger (centroid) estimation of individual gamma-ray events yielded spatial resolutions better than 100 um; a result previously achievable only with pixellated semiconductor detector arrays. After proper calibration, depth-of-interaction (DOI) effects are corrected by performing maximum-likelihood 3D position and energy estimation of individual gamma-ray interactions.
机译:我们使用一种估计相互作用位置的方法来优于光分布的分布,研究了圆柱状CsI(Tl)单光子成像系统的空间分辨率。柱状闪烁体直接耦合到以2x2分档的512x512电子倍增CCD(EMCCD)相机(16 ur像素),以32 um像素采样。来自伽玛射线/闪烁体相互作用的光学光子在多个像素上采样。所得图像显示了原始交互作用点处的信号簇,Cs和I K X射线(最远数百微米)的簇以及准直仪K X射线的簇。同样明显的是,相互作用深度效应导致光分布的扩大。这些影响导致空间和能量分辨率下降。处理簇像素数据以更好地估计初始交互簇内的交互位置。对单个伽马射线事件的愤怒(质心)估计产生了优于100 um的空间分辨率;以前只有像素化半导体探测器阵列才能达到的结果。经过适当的校准后,可以通过执行最大似然3D位置和单个伽马射线相互作用的能量估计来校正相互作用深度(DOI)效果。

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