Sol-gel matrices are promisign host materials for potential chemical and biosensor applications. previous studies have focused on modifed sol-gel routes using alkoxides for encapsulation of enzymes. However the formation of alcohol as a byproduct during hydrolysis and condensation reactions poses limitations. We report the immobilization of glucose oxidase and peroxidase in silica prespared by an aqueous route which may provide a more favorable environemtn for the biomolecules.
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