Directing growth cones of optic axons growing with laser scissors and laser tweezers

摘要

We have combined a laser scissors and a laser tweezers to study, (1) the response of nerve fiber growth cones to laser-induced damage on single axons, and (2) localized microfluidic flow generated by laser-driven spinning birefringentparticles. In the laser scissors study, sub-axotomy damage elicits a growth cone response whether damage is on the sameor an adjacent axon. In laser tweezers study, the axon growth cones turn in response to the optically driven microfluidicflow. In summary, both the laser scissors and the laser tweezers studies elicit growth cone turning responses.o© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.