Analytical model for sub-diffusive light reflection and the application to spatial frequency-domain imaging

摘要

We present here an analytical model describing light reflectance at an arbitrary source-detector separation covering both sub-diffusive and diffusion regimes for forward-peaked scattering media such as biological tissue. The model incorporates the small-angle scattering approximation (SAA) to radiative transfer for sub-diffusive light reflectance at a source-detector separation less than one single scattering length where the details of the phase function of light scattering dominate. The performance of the model is verified by Monte Carlo simulations. We also present the application of this analytical model in spatial frequency-domain imaging, in particular, when the spatial frequency is pushed below the reduced scattering coefficient.