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Monitoring cerebral tissue oxygen saturation during surgery: a clinician's perspective

机译:在手术过程中监测脑组织氧饱和度:临床医生的观点

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Organ protection and physiology optimization are important goals when taking care of anesthetized patients undergoing surgery. Postoperative cognitive dysfunction and perioperative stroke are unwarranted potential outcomes. Neurovascular coupling, the match between cerebral metabolic demand and substrate supply, should be regarded as the essential cerebral physiology which needs to be monitored during surgery. The brain-targeting near-infrared spectroscopy (N1RS) technology has the potential to fulfill this goal. Proposition of why and how to monitor essential cerebral physiology via advanced N1RS technologies is discussed. We also discussed the limits of the current NIRS technologies which merely measure cerebral tissue oxygen saturation in pooled cerebral arterial, capillary, and venous blood.
机译:在照顾接受手术的麻醉患者时,器官保护和生理优化是重要的目标。术后认知功能障碍和围手术期卒中是不必要的潜在结果。脑血管代谢需求与底物供应之间的匹配,应被视为神经血管耦合,这是在手术过程中需要监测的基本脑生理。靶向大脑的近红外光谱(N1RS)技术具有实现这一目标的潜力。讨论了为什么以及如何通过先进的N1RS技术监测基本的大脑生理的主张。我们还讨论了当前NIRS技术的局限性,这些技术仅能测量合并的脑动脉,毛细血管和静脉血中的脑组织氧饱和度。

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