A compact laparoscope type radiation source for the pin-point cancer treatment using a femto-second laser

摘要

Focusing a femto-second laser (1 mJ/pulse repetition 1 kHz) on a special tape, a strong radiation consisting of the electron beam of ～ 200 keV and X-rays of ～ 6.4 keV (5 %) has been generated. It has been verified that the radiation source is sufficient to kill the tumor cells and the DNA laddering structure in the in-vivo test is obtained. More test implanting the tumor under the skin of mouse and irradiating the laser-generated radiation, we have shown the radiation has a clear powerful therapeutic capability. For about 80 % of mice irradiated, their tumor disappeared. For further clinical test use, a compact laparoscope-type unit mounted on an articulated arm has been constructed and it can generate the necessary amount of the radiation dose.