Hyperselective and Targeted Separation of Analytes Using Dynamic Multiple Equilibrium Gradients (DMEG) Approach

摘要

Separation of closely related analytes can be significantly enhanced by introducing a new dynamic multiple equilibrium gradients (DMEG) approach. Namely, low-voltages applied as running waveforms to specifically designed grids of electrodes microfabricated along the separation channel (e.g. a thin capillary) can increase peak capacity and separation of molecules in complex mixtures.