NEW CHIRAL CATALYSTS FOR C-C-BOND FORMATIONS

摘要

This overview is mainly focused on the use of chiral catalysts for asymmetric reactions in organic synthesis. Recently, a new ligand type having sulfur as the sole stereogenic element has been introduced, and use of such, sulfoximines' leads to products with excellent enantioselectivities in asymmetric C-C-bond forming reactions and imine hydrogenations. For large-scale applications, the synthetic access of sulfoximines had to be improved. In addition, metal-free asymmetric anhydride openings with alkaloids as reaction mediators will be presented.