Better, faster, stronger: Shared resources and biomolecular feedback considerations for better engineering of bacterial cells

摘要

In particular, I will present some recent work on the development of various biomolecular feedback mechanisms in bacterial cells (mainly E. coli) that we use to answer the above questions. Our envisioned target applications for these novel designs include robust cell-based therapies, more efficient biosynthesis, and scale-up in synthetic biology and biotechnology.